Articles with "desferrioxamine biosynthesis" as a keyword



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Siderophore Synthetase DesD Catalyzes N-to-C Condensation in Desferrioxamine Biosynthesis.

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Published in 2023 at "ACS chemical biology"

DOI: 10.1021/acschembio.3c00167

Abstract: Desferrioxamine siderophores are assembled by the nonribosomal-peptide-synthetase-independent siderophore (NIS) synthetase enzyme DesD via ATP-dependent iterative condensation of three N1-hydroxy-N1-succinyl-cadaverine (HSC) units. Current knowledge of NIS enzymology and the desferrioxamine biosynthetic pathway does not account for… read more here.

Keywords: condensation; desd catalyzes; desferrioxamine biosynthesis; desferrioxamine ... See more keywords