Desialylation of O-glycans on glycoprotein Ibα drives receptor signaling and platelet clearance
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DOI: 10.3324/haematol.2019.240440
Abstract: During infection neuraminidase desialylates platelets and induces their rapid clearance from circulation. The underlying molecular basis, particularly the role of platelet glycoprotein (GP)Ibα therein, is not clear. Utilizing genetically altered mice, we report that the… read more here.
Keywords: platelet clearance; desialylation glycans; gpib; clearance ... See more keywords