Articles with "design artificial" as a keyword



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Interactions between polyoxometalates and biological systems: from drug design to artificial enzymes.

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Published in 2018 at "Current opinion in biotechnology"

DOI: 10.1016/j.copbio.2018.11.013

Abstract: Polyoxometalates have long been studied in a variety of biological applications. Interactions between the highly charged POM molecules and biological molecules frequently occur through hydrogen-bonding and electrostatic interactions. Tellurium-centred Anderson-Evans POMs show exceptional promise as… read more here.

Keywords: polyoxometalates biological; design artificial; biological systems; drug design ... See more keywords

Bioinspired Design of Artificial Signaling Systems.

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Published in 2022 at "Biochemistry"

DOI: 10.1021/acs.biochem.2c00368

Abstract: Natural systems use weak interactions and avidity effects to give biological systems high specificity and signal-to-noise ratios. Here we describe design principles for engineering fusion proteins that target therapeutic fusion proteins to membrane-bound signaling receptors… read more here.

Keywords: signaling systems; artificial signaling; design artificial; affinity ... See more keywords
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Search for Catalysts by Inverse Design: Artificial Intelligence, Mountain Climbers, and Alchemists.

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Published in 2019 at "Chemical reviews"

DOI: 10.1021/acs.chemrev.8b00759

Abstract: In silico catalyst design is a grand challenge of chemistry. Traditional computational approaches have been limited by the need to compute properties for an intractably large number of possible catalysts. Recently, inverse design methods have… read more here.

Keywords: catalysts inverse; search catalysts; design artificial; inverse design ... See more keywords

Structure-Guided Design of Artificial Transcription Factor for a Progesterone Biosensor.

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Published in 2025 at "ACS synthetic biology"

DOI: 10.1021/acssynbio.5c00488

Abstract: Transcription factors (TFs) can be used in genetic circuits and biosensors in the field of synthetic biology. Traditionally, TFs derived from prokaryotic organisms are transferred to more complex eukaryotic cells to achieve gene control; however,… read more here.

Keywords: biosensor; progesterone; biology; design artificial ... See more keywords

Design of artificial neural network hardware accelerator

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Published in 2023 at "Journal of Instrumentation"

DOI: 10.1088/1748-0221/18/04/c04013

Abstract: We present a design of the scalable processor capable of providing an artificial neural network (ANN) functionality and in-house developed tools for automatic conversion of an ANN model designed with the TensorFlow library into an… read more here.

Keywords: neural network; network; hardware; design artificial ... See more keywords

Species-specific design of artificial promoters by transfer-learning based generative deep-learning model

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Published in 2024 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkae429

Abstract: Native prokaryotic promoters share common sequence patterns, but are species dependent. For understudied species with limited data, it is challenging to predict the strength of existing promoters and generate novel promoters. Here, we developed PromoGen,… read more here.

Keywords: species specific; deep learning; design artificial; model ... See more keywords