Design of a Chiral Ionic Liquid System for the Enantioselective Addition of Diethylzinc to Aldehydes
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201701426
Abstract: An important contribution to the field of asymmetric catalysis is described in this work, as it merges the search for new ligands that can provide high performance in asymmetric catalysis with the extremely important and… read more here.
Keywords: system; enantioselective addition; design chiral; chiral ionic ... See more keywords
Design of Chiral NHC‐Carboxylates as Potential Ligands for Pd‐Catalyzed Enantioselective C−H Activation
Sign Up to like & getrecommendations! Published in 2021 at "Helvetica Chimica Acta"
DOI: 10.1002/hlca.202100015
Abstract: Despite numerous efforts, the synthesis of scalemic carbo- and heterocycles through Pd0-catalyzed C(sp3)-H activation employing chiral ancillary ligands or chiral bases is still limited. Inspired by the recently reported outstanding performance of IBiox-type NHC ligands… read more here.
Keywords: activation; nhc carboxylates; design chiral; nhc ... See more keywords
Rational Design of Chiral Tridentate Ligands: Bifunctional Cobalt(II) Complex/Hydrogen Bond for Enantioselective Michael Reactions.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c01435
Abstract: Bifunctional chiral tridentate bis(pyrroloimidazolone)pyridine (PyBPI) ligands have been designed, synthesized, and applied in an asymmetric Michael addition. With a 0.05 mol % PyBPI-Co(II) complex, β,γ-unsaturated α-keto esters reacted with 4-hydroxycoumarin to give the adducts in… read more here.
Keywords: tridentate; chiral tridentate; tridentate ligands; michael ... See more keywords
Modular Design of Chiral Conjugate-Base-Stabilized Carboxylic Acids: Catalytic Enantioselective [4+2] Cycloadditions of Acetals.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.0c07212
Abstract: Readily available 1,2-amino alcohols provide the framework for a new generation of chiral carboxylic acid catalysts that rival the acidity of the widely used chiral phosphoric acid catalyst (S)-TRIP. Covalently linked thiourea sites stabilize the… read more here.
Keywords: chiral conjugate; modular design; conjugate; design chiral ... See more keywords
Intelligent design of the chiral metasurfaces for flexible targets: combining a deep neural network with a policy proximal optimization algorithm.
Sign Up to like & getrecommendations! Published in 2022 at "Optics express"
DOI: 10.1364/oe.471629
Abstract: Recently, deep reinforcement learning (DRL) for metasurface design has received increased attention for its excellent decision-making ability in complex problems. However, time-consuming numerical simulation has hindered the adoption of DRL-based design method. Here we apply… read more here.
Keywords: metasurfaces flexible; deep neural; chiral metasurfaces; design ... See more keywords