Articles with "design cytotoxicity" as a keyword



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Design, cytotoxicity and toxicity of new thiophene and thieno [2,3-b] pyridine derivatives

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Published in 2017 at "Medicinal Chemistry Research"

DOI: 10.1007/s00044-017-1780-6

Abstract: Novel thiophene derivatives 3a–f were synthesized by using the 3-oxo-3-propanenitrile derivatives 1a–c with triethylamine, elemental sulfur and either of malononitrile or ethyl cyanoacetate. Compounds 3a, 3c, and 3e were reacted with ethyl cyanoacetate to give… read more here.

Keywords: thiophene; design cytotoxicity; cancer; thieno pyridine ... See more keywords