Evolution-guided protein design of IscB for persistent epigenome editing in vivo.
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DOI: 10.1038/s41587-025-02655-3
Abstract: Naturally existing enzymes have been adapted for a variety of molecular technologies, with enhancements or modifications to the enzymes introduced to improve the desired function; however, it is difficult to engineer variants with enhanced activity… read more here.
Keywords: protein design; guided protein; evolution guided; design iscb ... See more keywords