Toward the Design of Ligands Selective for the C-Terminal Domain of TEADs.
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DOI: 10.1021/acs.jmedchem.2c00075
Abstract: The Hippo signaling pathway plays a fundamental role in the control of organ growth, cell proliferation, and stem cell characters. TEADs are the main transcriptional output regulators of the Hippo signaling pathway and bind to… read more here.
Keywords: terminal domain; selective terminal; ligands selective; design ligands ... See more keywords