Design of minibinder proteins as universal antagonists against canine and human TNFα
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DOI: 10.1038/s42003-025-09030-7
Abstract: In this study, we resolve the complex structure of canine TNFα (cTNFα) trimer bound to nanobody molecules at a resolution of 3.1 Å using cryo-electron microscopy. Structural comparison between cTNFα and human TNFα (hTNFα) reveals that… read more here.
Keywords: human tnf; design minibinder; ctnf; tnf ... See more keywords