Circularly Permuted Fluorogenic Proteins for the Design of Modular Biosensors.
Sign Up to like & getrecommendations! Published in 2018 at "ACS chemical biology"
DOI: 10.1021/acschembio.8b00417
Abstract: Fluorescent reporters are essential components for the design of optical biosensors that are able to image intracellular analytes in living cells. Herein, we describe the development of circularly permuted variants of Fluorescence-Activating and absorption-Shifting Tag… read more here.
Keywords: design modular; fluorogenic proteins; permuted fluorogenic; biosensors circularly ... See more keywords
Design of modular autoproteolytic gene switches responsive to anti-coronavirus drug candidates.
Sign Up to like & getrecommendations! Published in 2021 at "Nature communications"
DOI: 10.1038/s41467-021-27072-3
Abstract: The main (Mpro) and papain-like (PLpro) proteases encoded by SARS-CoV-2 are essential to process viral polyproteins into functional units, thus representing key targets for anti-viral drug development. There is a need for an efficient inhibitor… read more here.
Keywords: design modular; autoproteolytic gene; drug candidates; drug ... See more keywords
Optimal Design of Modular Electrical Infrastructure for Large-Scale Electric Bus Depots
Sign Up to like & getrecommendations! Published in 2023 at "IEEE Access"
DOI: 10.1109/access.2023.3243727
Abstract: Owing to the immense climate changes recently, the city of Hamburg has decided to allow the purchase of only emission-free buses for public transportation. Meanwhile, Hamburg focuses on the implementation of electric buses. For this… read more here.
Keywords: infrastructure; bus depots; design modular; electric bus ... See more keywords