Strategic design of peptide‐decorated aligned nanofibers impregnated with triiodothyronine for neural regeneration
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.2822
Abstract: Nerve injuries are often debilitating as its regeneration occurs in a slow and laborious manner. Remediation of nerve injury is a colossal task as functional restoration in larger gaps seldom occurs due to the complex… read more here.
Keywords: peptide decorated; regeneration; strategic design; nerve ... See more keywords
Methodological advances in the design of peptide-based vaccines.
Sign Up to like & getrecommendations! Published in 2022 at "Drug discovery today"
DOI: 10.1016/j.drudis.2022.03.004
Abstract: The tremendous advances in genomics, recombinant DNA technology, bioengineering and nanotechnology, in conjunction with the development of high-end computations, have been instrumental in the process of rational design of peptide-based vaccines. The use of peptide… read more here.
Keywords: based vaccines; design peptide; peptide based; methodological advances ... See more keywords
Design of peptide-containing N5-unmodified neutral flavins that catalyze aerobic oxygenations† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc01933e
Sign Up to like & getrecommendations! Published in 2017 at "Chemical Science"
DOI: 10.1039/c7sc01933e
Abstract: The first flavoenzyme-mimetic aerobic oxygenations catalyzed by N5-unmodified neutral flavin were realized with flavopeptides (Fl-Pep) rationally designed by computational calculations. read more here.
Keywords: containing unmodified; aerobic oxygenations; neutral flavins; peptide containing ... See more keywords
De novo design of peptide binders to conformationally diverse targets with contrastive language modeling
Sign Up to like & getrecommendations! Published in 2024 at "Science Advances"
DOI: 10.1101/2023.06.26.546591
Abstract: Designing binders to target undruggable proteins presents a formidable challenge in drug discovery, requiring innovative approaches to overcome the lack of putative binding sites. Recently, generative models have been trained to design binding proteins via… read more here.
Keywords: conformationally diverse; design peptide; language; design ... See more keywords