Fabrication of efavirenz loaded nano-formulation using quality by design (QbD) based approach: Exploring characterizations and in vivo safety
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2020.101545
Abstract: Abstract Quality by design (QbD) approach was practically applied in fabrication of nanostructured lipid carrier (NLC) encapsulating efavirenz (EF) to ensure the quality in product. Initially, risk factors were categorized based on risk priority number… read more here.
Keywords: design qbd; fabrication; quality design; approach ... See more keywords
Olaparib Process Development Employing Quality by Design (QbD) Principles
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DOI: 10.1021/acsomega.4c01293
Abstract: This study focuses on multivariate experimental design and statistical analysis to optimize the process of Olaparib 1. Quality by design (QbD) methodology was adopted for optimization of the Olaparib process consisting of three reaction steps:… read more here.
Keywords: process; quality design; design qbd; olaparib process ... See more keywords
Formulation of semi solid dosage forms for topical application utilizing quality by design (QbD) approach
Sign Up to like & getrecommendations! Published in 2025 at "Drug Development and Industrial Pharmacy"
DOI: 10.1080/03639045.2025.2498521
Abstract: Abstract Objective Over the last few decades, there have been advancements in our comprehension of the design and development of topical semisolid formulations; however, they still follow an empirical development. Our study focuses on building… read more here.
Keywords: quality; formulation; quality design; design qbd ... See more keywords
Optimization of a Coupling Process for Insulin Degludec According to a Quality by Design (QbD) Paradigm
Sign Up to like & getrecommendations! Published in 2018 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-018-1032-1
Abstract: This case study described a successful application of the quality by design (QbD) principles to a coupling process development of insulin degludec. Failure mode effects analysis (FMEA) risk analysis was first used to recognize critical… read more here.
Keywords: coupling process; insulin; design qbd; quality design ... See more keywords
Quality by Design (QbD) Approach for a Nanoparticulate Imiquimod Formulation as an Investigational Medicinal Product
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DOI: 10.3390/pharmaceutics15020514
Abstract: The present article exemplifies the application of the concept of quality by design (QbD) for the systematic development of a nanoparticulate imiquimod (IMQ) emulsion gel formulation as an investigational medicinal product (IMP) for evaluation in… read more here.
Keywords: quality; design qbd; design; nanoparticulate imiquimod ... See more keywords