What Are the Most Powerful Immunogen Design Vaccine Strategies? Reverse Vaccinology 2.0 Shows Great Promise.
Sign Up to like & getrecommendations! Published in 2017 at "Cold Spring Harbor perspectives in biology"
DOI: 10.1101/cshperspect.a030262
Abstract: Functional antibodies, i.e., those with antipathogen activity in in vitro assays, are generally the best correlate of vaccine protection. Mimics of natural infection, including live attenuated and killed pathogens, which induce such antibodies in vivo,… read more here.
Keywords: functional antibodies; design vaccine; immunogen design; powerful immunogen ... See more keywords