Evaluation of Rationally Designed Label-free Stem-loop DNA Probe Opening in the Presence of miR-21 by Circular Dichroism and Fluorescence Techniques
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DOI: 10.1038/s41598-020-60157-5
Abstract: The characteristic features of stem-loop structured probes make them robust tools to detect targets with high sensitivity and selectivity. The basis of the hairpin based sensors operation is a conformational change that occurs upon hybridization… read more here.
Keywords: probe; designed label; target; spectroscopy ... See more keywords