Injection of Pharmaceuticals Designed for Oral Use: Harms Experienced and Effective Harm Reduction Through Filtration.
Sign Up to like & getrecommendations! Published in 2017 at "Current topics in behavioral neurosciences"
DOI: 10.1007/7854_2016_470
Abstract: Several pharmaceutical products are liable to 'abuse' or use outside their prescription, which frequently involves their injection. Examples are slow-release forms of morphine and oxycodone, and sublingual buprenorphine. During injection preparation, the drug is extracted… read more here.
Keywords: use; filtration; drug; injection pharmaceuticals ... See more keywords
A rationally designed oral vaccine induces immunoglobulin A in the murine gut that directs the evolution of attenuated Salmonella variants.
Sign Up to like & getrecommendations! Published in 2021 at "Nature microbiology"
DOI: 10.1038/s41564-021-00911-1
Abstract: The ability of gut bacterial pathogens to escape immunity by antigenic variation-particularly via changes to surface-exposed antigens-is a major barrier to immune clearance1. However, not all variants are equally fit in all environments2,3. It should… read more here.
Keywords: induces immunoglobulin; oral vaccine; vaccine induces; antigen ... See more keywords