Designer Benzodiazepines: Another Class of New Psychoactive Substances.
Sign Up to like & getrecommendations! Published in 2018 at "Handbook of experimental pharmacology"
DOI: 10.1007/164_2018_154
Abstract: Benzodiazepines have been introduced as medical drugs in the 1960s. They replaced the more toxic barbiturates, which were commonly used for treatment of anxiety or sleep disorders at the time. However, benzodiazepines show a high… read more here.
Keywords: designer; another class; designer benzodiazepines; class new ... See more keywords
Urine analysis of 28 designer benzodiazepines by liquid chromatography–high-resolution mass spectrometry
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Mass Spectrometry"
DOI: 10.1016/j.clinms.2018.08.004
Abstract: Abstract Hundreds of new psychoactive substances (NPS) covering most drugs-of-abuse classes have been introduced to the recreational drug market in recent years. One class of NPS drugs that has become more common recently is “designer”… read more here.
Keywords: high resolution; designer benzodiazepines; mass spectrometry; mass ... See more keywords
Fast and Sensitive Method for the Determination of 17 Designer Benzodiazepines in Hair by Liquid Chromatography-Tandem Mass Spectrometry.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of analytical toxicology"
DOI: 10.1093/jat/bkac044
Abstract: In recent years, identification and analysis of designer benzodiazepines have become a challenge in forensic toxicology. These substances are analogues of the classic benzodiazepines, but their pharmacology is not well known, and many of them… read more here.
Keywords: toxicology; fast sensitive; hair; designer ... See more keywords
A Fatal Case Report Resulting from the Abuse of the Designer Benzodiazepines Clonazolam and Flualprazolam in Conjunction with Dried Opium Poppy Pods.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of analytical toxicology"
DOI: 10.1093/jat/bkac098
Abstract: Toxicologists are often confronted with the abuse of multiple drugs and are obliged to decide which compound may have been the cause of death. We report on a 21-year-old man (182 cm, 84 kg), who… read more here.
Keywords: dried opium; opium poppy; report; designer ... See more keywords
Characterization of Flunitrazolam, a New Designer Benzodiazepine, in Oral Fluid After a Controlled Single Administration.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of analytical toxicology"
DOI: 10.1093/jat/bky012
Abstract: To the Editor: Benzodiazepines are a class of drugs widely prescribed for the treatment of anxiety, insomnia, epilepsy, muscle spasms or alcohol withdrawal. Reactive to GABA type A receptors, benzodiazepines have a rapid and weakly… read more here.
Keywords: designer; administration; oral fluid; designer benzodiazepines ... See more keywords
Designer benzodiazepines' activity on opioid receptors: a docking study.
Sign Up to like & getrecommendations! Published in 2022 at "Current pharmaceutical design"
DOI: 10.2174/1381612828666220510153319
Abstract: BACKGROUND Previous studies have reported that benzodiazepines (BZDs) seem to enhance euphoric and reinforcing properties of opioids in opioid users so that a direct effect on opioid receptors has been postulated together with possible synergistic… read more here.
Keywords: benzodiazepines activity; opioid receptors; activity; designer benzodiazepines ... See more keywords
Determination of traditional and designer benzodiazepines in urine through LC-MS/MS.
Sign Up to like & getrecommendations! Published in 2022 at "Current pharmaceutical design"
DOI: 10.2174/1381612828666220831103224
Abstract: BACKGROUND The detection of new designer benzodiazepines in biological fluids and tissues, together with the traditional ones, could represent an important analytical update for laboratories performing clinical and forensic toxicological analysis. OBJECTIVE A liquid chromatography… read more here.
Keywords: benzodiazepines urine; designer; designer benzodiazepines; determination traditional ... See more keywords