Abstract LB-B23: Prodrug activation by designer enzyme targeted to CD123-expressing tumors
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DOI: 10.1158/1535-7163.targ-17-lb-b23
Abstract: We propose the combination of tumor-targeting antibodies with a drug-activating enzyme and a prodrug, which could be expected to give synergy and enhanced therapeutic efficacy in the treatment of leukemia and other malignancies. We have… read more here.
Keywords: designer; prodrug activation; enzyme targeted; designer enzyme ... See more keywords