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Designing Cell-Permeable Macrocyclic Peptides.

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0 Published in 2019 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-9504-2_3

Abstract: Peptides provide an attractive modality for targeting challenging drug targets such as intracellular protein-protein interactions. Unfortunately, peptides are generally impermeable to the cell membrane and inherently susceptible to proteolytic degradation in vivo. Macrocyclization of peptides… read more here.

Keywords: designing cell; cell permeable; macrocyclic peptides; cell penetrating ... See more keywords