Embracing model-based designs for dose-finding trials
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DOI: 10.1038/bjc.2017.186
Abstract: Background:Dose-finding trials are essential to drug development as they establish recommended doses for later-phase testing. We aim to motivate wider use of model-based designs for dose finding, such as the continual reassessment method (CRM).Methods:We carried… read more here.
Keywords: model based; based designs; designs dose; dose finding ... See more keywords