Fabrication of magnetic iron oxide-supported copper oxide nanoparticles (Fe3O4/CuO): modified screen-printed electrode for electrochemical studies and detection of desipramine
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DOI: 10.1039/d0ra02380a
Abstract: The present investigation examines a sensitive electrochemical technique to detect desipramine through Fe3O4/CuO nanoparticles (NPs). Fe3O4/CuO NPs were synthesized via a coprecipitation procedure, and the products were characterized via energy disperse spectroscopy, X-ray diffraction, transmission… read more here.
Keywords: cuo; microscopy; desipramine; fe3o4 cuo ... See more keywords
A randomized placebo-controlled trial of desipramine, cognitive behavioral therapy, and active placebo therapy for low back pain.
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DOI: 10.1097/j.pain.0000000000001834
Abstract: This clinical trial evaluated the independent and combined effects of a tricyclic antidepressant (desipramine) and cognitive behavioral therapy (CBT) for chronic back pain relative to an active placebo treatment. Participants (n=142) were patients experiencing daily… read more here.
Keywords: therapy; trial; back pain; desipramine ... See more keywords
Desipramine enhances the stability of atherosclerotic plaque in rabbits monitored with molecular imaging
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DOI: 10.1371/journal.pone.0283612
Abstract: Acid sphingomyelinase (ASM) promotes atherogenesis and acute cardiovascular events. We previously demonstrated ASM inhibitor desipramine attenuated oxidized-LDL-induced macrophage apoptosis in vitro. Here, we aim to determine whether ASM-mediated apoptosis in plaque improves stability in vivo.… read more here.
Keywords: atherosclerotic plaque; apoptosis; desipramine; plaque ... See more keywords
Depression and/or PTSD Comorbidity Affects Response to Antidepressants in Those With Alcohol Use Disorder
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DOI: 10.3389/fpsyt.2021.768318
Abstract: Objective: Depression and post-traumatic stress disorder (PTSD) highly co-occur with alcohol use disorder (AUD). The comparative effects of noradrenergic vs. serotonergic antidepressants on drinking and depressive outcomes for those with AUD and co-occurring depression and/or… read more here.
Keywords: desipramine; depression ptsd; depression; group ... See more keywords