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   Articles with "desloratadine" as a keyword



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Screening and evaluation of fungal resources for loratadine metabolites

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recommendations! Published in 2018 at "Journal of Biosciences"

DOI: 10.1007/s12038-018-9797-7

Abstract: Loratadine is a selective inverse agonist of peripheral histamine H1-receptors. Microbial biotransformation gained a lot of attention for its ability to convert molecules to valuable medicinally active substances. The main objective of the present research… read more here.

Keywords: evaluation fungal; screening evaluation; resources loratadine; spectroscopy ... See more keywords
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Antiallergic Treatment of Bariatric Patients: Potentially Hampered Solubility/Dissolution and Bioavailability of Loratadine, but Not Desloratadine, Post-Bariatric Surgery.

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recommendations! Published in 2022 at "Molecular pharmaceutics"

DOI: 10.1021/acs.molpharmaceut.2c00292

Abstract: Gastrointestinal anatomical/physiological changes after bariatric surgery influence variables affecting the fate of drugs after ingestion, and medication management of these patients requires a thorough and complex mechanistic analysis. The aim of this research was to… read more here.

Keywords: desloratadine; dissolution; surgery; solubility ... See more keywords
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Efficiency and safety of desloratadine in combination with compound glycyrrhizin in the treatment of chronic urticaria: a meta-analysis and systematic review of randomised controlled trials

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recommendations! Published in 2021 at "Pharmaceutical Biology"

DOI: 10.1080/13880209.2021.1973039

Abstract: Abstract Context Desloratadine, an H1 receptor antagonist, is suggested as an effective first-line drug for chronic urticarial (CU). However, the efficacy of desloratadine alone is limited, and the recurrence rate of CU is relatively high.… read more here.

Keywords: compound glycyrrhizin; desloratadine; treatment; combination ... See more keywords
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Evaluation of Thermal-Induced Polymorphic Transformation on Desloratadine and Desloratadine-Benzoic Acid Salt

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recommendations! Published in 2020 at "Pharmaceutical Sciences"

DOI: 10.34172/ps.2020.59

Abstract: Background: Active pharmaceutical ingredients face a challenge in manufacturing due to adverse physicomechanical properties. Desloratadine (DES) form I exhibits poor mechanical behavior through the formation of capping during the tableting process. Salt formation from DES… read more here.

Keywords: polymorphic transformation; desloratadine; des des; transformation ... See more keywords
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Desloratadine Efficacy in Relation to GSTM1 and GSTT1 Polymorphic Genes in Chronic Spontaneous Urticaria

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recommendations! Published in 2022 at "Indian Journal of Dermatology"

DOI: 10.4103/ijd.ijd_546_17

Abstract: Background: The etiopathogeny of chronic spontaneous urticaria (CSU) is not well defined. Allelism in glutathione S-transferase GSTM1 and GSTT1 has been suggested as a risk factor. Desloratadine is the first-line treatment for this disease. Objective:… read more here.

Keywords: desloratadine; efficacy; treatment; gstm1 ... See more keywords