Loperamide-induced severe cardiotoxicity: a toxicokinetic and toxicodynamic analysis derived from a case series and the published literature
Sign Up to like & getrecommendations! Published in 2025 at "Clinical Toxicology"
DOI: 10.1080/15563650.2025.2459763
Abstract: Abstract Introduction Chronic loperamide overdose is associated with cardiotoxicity. We describe the toxicokinetics of loperamide and N-desmethyl loperamide, and their concentration–response relationship on cardiotoxicity in newly described and published cases. Materials and methods We obtained… read more here.
Keywords: loperamide desmethyl; desmethyl loperamide; cardiotoxicity; loperamide ... See more keywords