Desmoglein 1 Regulates Invadopodia by Suppressing EGFR/Erk Signaling in an Erbin-Dependent Manner
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Cancer Research"
DOI: 10.1158/1541-7786.mcr-18-0048
Abstract: Loss of the desmosomal cell–cell adhesion molecule, Desmoglein 1 (Dsg1), has been reported as an indicator of poor prognosis in head and neck squamous cell carcinomas (HNSCC) overexpressing epidermal growth factor receptor (EGFR). It has… read more here.
Keywords: egfr erk; cancer; erk signaling; desmoglein ... See more keywords
Immunization with desmoglein 3 induces non-pathogenic autoantibodies in mice
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DOI: 10.1371/journal.pone.0259586
Abstract: Background Pemphigus vulgaris (PV) is a rare autoimmune blistering disease characterized by the development of autoantibodies targeting desmoglein (Dsg) 3, but also against Dsg1 in mucocutaneous disease. Given that existing PV animal models only recapitulate… read more here.
Keywords: sjl; immunization; non pathogenic; disease ... See more keywords