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Published in 2019 at "Journal of neuropathology and experimental neurology"
DOI: 10.1093/jnen/nlz086
Abstract: MAPK pathway activation has been recurrently observed in desmoplastic infantile ganglioglioma/astrocytoma (DIG/DIA) with reported disproportionally low mutation allele frequencies relative to the apparent high tumor content, suggesting that MAPK pathway alterations may be subclonal. We…
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Keywords:
desmoplastic infantile;
mapk pathway;
neuroepithelial tumor;
macrophage ... See more keywords
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Published in 2020 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noaa222.418
Abstract: Abstract Desmoplastic infantile astrocytoma (DIA) and desmoplastic infantile ganglioglioma (DIG) are benign glioneuronal tumors that typically occur in infants, involve the superficial cerebral cortex, and have an excellent prognosis. DIA/DIG are a distinct molecular entity…
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Keywords:
fusion;
desmoplastic infantile;
infantile;
ppp1cb alk ... See more keywords
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Published in 2022 at "Neuropathology and Applied Neurobiology"
DOI: 10.1111/nan.12801
Abstract: Desmoplastic infantile astrocytomas and gangliogliomas (DIA/DIGs) are rare brain tumours of infancy. A distinctive feature of their histopathology is a combination of low‐grade and high‐grade features. Most DIA/DIGs can be surgically resected and have a…
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Keywords:
high grade;
grade high;
grade;
desmoplastic infantile ... See more keywords
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Published in 2018 at "Molecular Cancer Research"
DOI: 10.1158/1541-7786.mcr-17-0507
Abstract: Desmoplastic infantile ganglioglioma (DIG) and desmoplastic infantile astrocytoma (DIA) are extremely rare tumors that typically arise in infancy; however, these entities have not been well characterized in terms of genetic alterations or clinical outcomes. Here,…
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Keywords:
dig;
dig dia;
desmoplastic infantile;
dia distinct ... See more keywords
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Published in 2019 at "American Journal of Neuroradiology"
DOI: 10.3174/ajnr.a6226
Abstract: SUMMARY: Desmoplastic infantile tumors are rare supratentorial brain tumors that occur in pediatric patients. Desmoplastic infantile tumors are made up of 2 subtypes: desmoplastic infantile gangliogliomas and desmoplastic infantile astrocytomas. Desmoplastic infantile tumors are often…
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Keywords:
infantile tumors;
mixed solid;
solid cystic;
desmoplastic infantile ... See more keywords
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Published in 2019 at "Oman Medical Journal"
DOI: 10.5001/omj.2019.84
Abstract: Desmoplastic infantile ganglioglioma (DIG) is a rare supratentorial brain tumor, which is usually diagnosed before the age of two and has a favorable prognosis. To date, only a few cases have been reported in the…
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Keywords:
infantile ganglioglioma;
desmoplastic infantile;
arachnoid cyst;