N-Heterocyclic carbene catalyzed desymmetrization of diols: access to enantioenriched oxindoles having a C3-quaternary stereocenter.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical communications"
DOI: 10.1039/d3cc00489a
Abstract: Herein, we describe an effective strategy for enantioselective synthesis of oxindoles having a C3-quaternary stereocenter via N-heterocyclic carbene (NHC) catalyzed desymmetrization of diols. The process is based on the catalytic asymmetric transfer acylation of primary… read more here.
Keywords: catalyzed desymmetrization; quaternary stereocenter; desymmetrization diols; oxindoles quaternary ... See more keywords
Enantioselective Desymmetrization of 1,3-Diols by a Chiral DMAP Derivative
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DOI: 10.1246/cl.180697
Abstract: We developed an enantioselective desymmetrization of 1,3-diols by a chiral N,N-dimethyl-4-aminopyridine (DMAP) derivative containing a 1,1′-binaphthyl with tert-alcohol units. The reactions require... read more here.
Keywords: enantioselective desymmetrization; dmap derivative; chiral dmap; desymmetrization diols ... See more keywords