Ir-Catalyzed Atroposelective Desymmetrization of Heterobiaryls: Hydroarylation of Vinyl Ethers and Bicycloalkenes.
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DOI: 10.1021/jacs.9b12858
Abstract: A highly regio, diastereo- and enantioselective, scalable Ir-catalyzed hydroarylation of electron rich acyclic and tensioned cyclic olefins with heterobiaryls is described. The reaction of acyclic vinyl ethers, dihydrofuran and norbornenes with a variety of aryl… read more here.
Keywords: hydroarylation; atroposelective desymmetrization; vinyl ethers; desymmetrization heterobiaryls ... See more keywords