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Oxidative Desymmetrization of Isoindolines Realized by tert-Butyl Nitrite (TBN) Initiated Radical sp3 C–H Activation Relay (CHAR)

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Published in 2021 at "Synthesis"

DOI: 10.1055/s-0040-1706010

Abstract: An oxidative desymmetrization of isoindolines was realized by TBN initiated radical sp3 C–H activation relay (CHAR), providing a series of ω-hydroxylactams in high yields. This reaction exhibits broad substrate scope and functional group tolerance, and… read more here.

Keywords: initiated radical; desymmetrization isoindolines; oxidative desymmetrization; desymmetrization ... See more keywords