Abstract 2410: RIPK1-mediated induction of mitophagy compromises the viability of extracellular matrix-detached cells
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DOI: 10.1158/1538-7445.am2018-2410
Abstract: For cancer cells to survive during ECM-detachment, they must inhibit anoikis and rectify metabolic deficiencies that cause non-apoptotic cell death. Previous studies in ECM-detached cells have linked non-apoptotic cell death to ROS generation, although the… read more here.
Keywords: ripk1 mediated; ripk1; mitophagy; detached cells ... See more keywords