Detecting T cell activation using a varying dimension Bayesian model
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Applied Statistics"
DOI: 10.1080/02664763.2017.1290789
Abstract: ABSTRACT The detection of T cell activation is critical in many immunological assays. However, detecting T cell activation in live tissues remains a challenge due to highly noisy data. We developed a Bayesian probabilistic model… read more here.
Keywords: activation using; model; cell activation; cell ... See more keywords
Detecting T‐cell receptor clonality in patients with severe atopic dermatitis refractory to dupilumab
Sign Up to like & getrecommendations! Published in 2024 at "Journal of the European Academy of Dermatology and Venereology"
DOI: 10.1111/jdv.20053
Abstract: Trials and real‐life studies demonstrated clinically meaningful improvements of disease activity in the majority of patients with moderate to severe atopic dermatitis (AD) treated with the anti‐IL‐4RA‐antibody dupilumab. However, misdiagnosis or confounding skin diseases in… read more here.
Keywords: detecting cell; atopic dermatitis; severe atopic; dupilumab ... See more keywords
Detecting T-cell clonal expansions and quantifying clone survival using deep profiling of immune repertoires
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2024.1321603
Abstract: An individual’s T-cell repertoire constantly changes under the influence of external and internal factors. Cells that do not receive a stimulatory signal die, while those that encounter and recognize a pathogen or receive a co-stimulatory… read more here.
Keywords: survival; detecting cell; cell clonal; cell ... See more keywords