Detecting and Rescuing Stalled Ribosomes.
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DOI: 10.1016/j.tibs.2021.03.008
Abstract: Ribosomes that stall inappropriately during protein synthesis harbor proteotoxic components linked to cellular stress and neurodegenerative diseases. Molecular mechanisms that rescue stalled ribosomes must selectively detect rare aberrant translational complexes and process the heterogeneous components.… read more here.
Keywords: rescuing stalled; stalled ribosomes; detecting rescuing;