MSTD for Detecting Topological Domains from 3D Genomic Maps.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0301-7_4
Abstract: In this chapter, we introduce a generic and efficient method to identify multiscale topological domains (MSTD), including cis- and trans-interacting regions, from a variety of 3D genomic datasets. We first applied MSTD to detect promoter-anchored… read more here.
Keywords: detecting topological; mstd detecting; genomic maps; domains genomic ... See more keywords
Detecting topological variations of DNA at single-molecule level
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-018-07924-1
Abstract: In addition to their use in DNA sequencing, ultrathin nanopore membranes have potential applications in detecting topological variations in deoxyribonucleic acid (DNA). This is due to the fact that when topologically edited DNA molecules, driven… read more here.
Keywords: single molecule; dna; dna single; detecting topological ... See more keywords