Integrin activation enables rapid detection of functional Vδ1+ and Vδ2+ γδ T cells
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Immunology"
DOI: 10.1002/eji.202149682
Abstract: Conformational change of the β2 integrin lymphocyte function‐associated antigen 1 (LFA‐1) is an early marker of T cell activation. A protocol using the mAb clone m24 recognizing the active, extended high‐affinity conformation has been previously… read more here.
Keywords: activation; activation enables; detection; functional cells ... See more keywords
Scalable multiple changepoint detection for functional data sequences
Sign Up to like & getrecommendations! Published in 2021 at "Environmetrics"
DOI: 10.1002/env.2710
Abstract: We propose the Multiple Changepoint Isolation (MCI) method for detecting multiple changes in the mean and covariance of a functional process. We first introduce a pair of projections to represent the high and low frequency… read more here.
Keywords: changepoint; multiple changepoint; detection functional; changepoint detection ... See more keywords
Hybrid online sensor error detection and functional redundancy for systems with time-varying parameters.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of process control"
DOI: 10.1016/j.jprocont.2017.04.004
Abstract: Supervision and control systems rely on signals from sensors to receive information to monitor the operation of a system and adjust manipulated variables to achieve the control objective. However, sensor performance is often limited by… read more here.
Keywords: error detection; functional redundancy; system; detection functional ... See more keywords
Peptidyl arginine deiminases: detection and functional analysis of protein citrullination.
Sign Up to like & getrecommendations! Published in 2019 at "Current opinion in structural biology"
DOI: 10.1016/j.sbi.2019.01.024
Abstract: Citrullination is a post-translational modification of arginine that is catalyzed by the protein arginine deiminases (PADs). Abnormal citrullination is observed in many autoimmune diseases and cancers. Anti-citrullinated protein antibodies (ACPA) are hallmarks of RA and… read more here.
Keywords: peptidyl arginine; arginine deiminases; citrullination; protein citrullination ... See more keywords
Detection of Functional Communities in Networks of Randomly Coupled Oscillators Using the Dynamic-Mode Decomposition
Sign Up to like & getrecommendations! Published in 2021 at "Physical review. E"
DOI: 10.1103/physreve.104.044305
Abstract: Dynamic-mode decomposition (DMD) is a versatile framework for model-free analysis of time series that are generated by dynamical systems. We develop a DMD-based algorithm to investigate the formation of functional communities in networks of coupled,… read more here.
Keywords: functional communities; detection functional; dynamic mode; mode decomposition ... See more keywords
Disease Cluster Detection and Functional Characterization
Sign Up to like & getrecommendations! Published in 2020 at "IEEE Access"
DOI: 10.1109/access.2020.3013666
Abstract: Mechanisms underlying human diseases have been revealed with the development of molecular biology. The underlying molecular basis of disorders is valuable in prevention, diagnosis, and treatment. Decade-long efforts have been devoted to investigating disease–gene association… read more here.
Keywords: cluster detection; functional characterization; disease clusters; disease ... See more keywords