Detergent-Assisted Protein Digestion—On the Way to Avoid the Key Bottleneck of Shotgun Bottom-Up Proteomics
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DOI: 10.3390/ijms232213903
Abstract: Gel-free bottom-up shotgun proteomics is the principal methodological platform for the state-of-the-art proteome research. This methodology assumes quantitative isolation of the total protein fraction from a complex biological sample, its limited proteolysis with site-specific proteases,… read more here.
Keywords: assisted protein; bottom; detergent assisted; shotgun ... See more keywords