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Published in 2019 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.8b00427
Abstract: APOBEC3B (A3B) is a prominent source of mutation in many cancers. To date, it has been difficult to capture the native protein-DNA interactions that confer A3B's substrate specificity by crystallography due to the highly dynamic…
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Keywords:
determinants oligonucleotide;
binding site;
site;
oligonucleotide selectivity ... See more keywords