Genetic Determinants of P2Y12 Inhibitors and Clinical Implications.
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DOI: 10.1016/j.iccl.2016.08.010
Abstract: There is significant interpatient variability in clopidogrel effectiveness, which is due in part to cytochrome P450 (CYP) 2C19 genotype. Approximately 30% of individuals carry CYP2C19 loss-of-function alleles, which have been consistently shown to reduce clopidogrel… read more here.
Keywords: genetic determinants; cardiology; clinical implications; inhibitors clinical ... See more keywords