Articles with "determinants pharmacokinetic" as a keyword



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Genetic Determinants of the Pharmacokinetic Variability of Rifampin in Malawian Adults with Pulmonary Tuberculosis

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Published in 2017 at "Antimicrobial Agents and Chemotherapy"

DOI: 10.1128/aac.00210-17

Abstract: ABSTRACT Variable exposure to antituberculosis (TB) drugs, partially driven by genetic factors, may be associated with poor clinical outcomes. Previous studies have suggested an influence of the SLCO1B1 locus on the plasma area under the… read more here.

Keywords: genetic determinants; variability; adults pulmonary; rifampin ... See more keywords