Determination of the inhibition profiles of pyrazolyl–thiazole derivatives against aldose reductase and α‐glycosidase and molecular docking studies
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DOI: 10.1002/ardp.202000118
Abstract: Aldose reductase (AR) is the first and rate‐limiting enzyme of the polyol pathway, which converts glucose to sorbitol in an NADPH‐dependent reaction. α‐Glycosidase breaks down starch and disaccharides to glucose. Hence, inhibition of these enzymes… read more here.
Keywords: determination inhibition; glycosidase; aldose reductase; inhibition ... See more keywords
Lectin-based assay for the determination of the inhibition activity of small molecule inhibitors of neuraminidases.
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DOI: 10.1016/j.jbiotec.2020.11.016
Abstract: Small molecules inhibitors of neuraminidases (NAs) are ones of the most prospective molecules proposed for the treatment of influenza viruses. The determination of their inhibition activity in vitro is an important step during the development… read more here.
Keywords: determination inhibition; inhibitors neuraminidases; inhibition; inhibition activity ... See more keywords