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Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac258
Abstract: Abstract Lineage-determining transcription factors (LD-TFs) drive the differentiation of progenitor cells into a specific lineage. In CD4+ T cells, T-bet dictates differentiation of the TH1 lineage, whereas GATA3 drives differentiation of the alternative TH2 lineage.…
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Keywords:
bet;
lineage determining;
determining transcription;
gata3 ... See more keywords
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recommendations!
1
Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac452
Abstract: Abstract Analyzing single-cell transcriptomes promises to decipher the plasticity, heterogeneity, and rapid switches in developmental cellular state transitions. Such analyses require the identification of gene markers for semi-stable transition states. However, there are nontrivial challenges…
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Keywords:
lineage determining;
critical transition;
determining transcription;
single cell ... See more keywords