Chlorella Vulgaris‐Inspired Versatile Theranostic Nanoparticles for Specific Recognition and Detoxification to Copper (II) In Vitro and In Vivo
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202407241
Abstract: Specific recognition and detoxification for copper is the key step for the early diagnosis and treatment of various diseases such as neurodegenerative disease and Wilson's disease. Herein, a Chlorella vulgaris‐inspired versatile theranostic nanoparticles is facilely… read more here.
Keywords: specific recognition; recognition detoxification; theranostic nanoparticles; versatile theranostic ... See more keywords
Engineered‐Macrophage‐Escorted Rotaxane Nanoscavengers for Precise Diquat Detoxification
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Materials"
DOI: 10.1002/adma.202506466
Abstract: This study proposes a bioinspired on‐demand detoxification strategy addressing the critical need for efficient toxin poisoning therapies. Focusing on the high‐mortality herbicide diquat, an active toxin‐hunting paradigm is developed, diverging from passive methods like hemodialysis.… read more here.
Keywords: nanoscavengers precise; rotaxane nanoscavengers; macrophage escorted; escorted rotaxane ... See more keywords
Xenobiotic responses in insects.
Sign Up to like & getrecommendations! Published in 2022 at "Archives of insect biochemistry and physiology"
DOI: 10.1002/arch.21869
Abstract: Insects have evolved a powerful detoxification system to protect themselves against environmental and anthropogenic xenobiotics including pesticides and nanoparticles. The resulting tolerance to insecticides is an immense problem in agriculture. In this study, we summarize… read more here.
Keywords: detoxification; insects; responses insects; response ... See more keywords
Enhanced ammonia detoxification to urea in hepatocytes transduced with human aquaporin‐8 gene
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.27901
Abstract: Hepatic ammonia detoxification to urea is critical for the prevention of hyperammonemia and neurological damage. Hepatocyte mitochondrial aquaporin‐8 (AQP8) channels have been involved in ammonia‐derived ureagenesis. Herein, we studied whether the adenoviral gene transfer of… read more here.
Keywords: detoxification urea; haqp8; detoxification; enhanced ammonia ... See more keywords
Connecting Algal Polysaccharide Degradation to Formaldehyde Detoxification
Sign Up to like & getrecommendations! Published in 2022 at "Chembiochem"
DOI: 10.1002/cbic.202200269
Abstract: Formaldehyde is a toxic metabolite that is formed in large quantities during bacterial utilization of the methoxy sugar 6‐O‐methyl‐d‐galactose, an abundant monosaccharide in the red algal polysaccharide porphyran. Marine bacteria capable of metabolizing porphyran must… read more here.
Keywords: detoxification; formaldehyde; connecting algal; algal polysaccharide ... See more keywords
Cyclic Octapeptides Composed of Two Glutathione Units Outperform the Monomer in Lead Detoxification
Sign Up to like & getrecommendations! Published in 2022 at "Chemmedchem"
DOI: 10.1002/cmdc.202200152
Abstract: A rationally‐designed scaffold of cyclic octapeptides composed of two units of the natural tripeptide glutathione (GSH) was optimized to strongly and selectively capture toxic lead ions (Pb(II)). Using state‐of‐the‐art computational tools, a list of eleven… read more here.
Keywords: detoxification; octapeptides composed; cyclic octapeptides; glutathione ... See more keywords
Divergent Selection Promotes Intraspecific Genomic Differentiation in Spodoptera littoralis With Possible Involvement in Detoxification
Sign Up to like & getrecommendations! Published in 2025 at "Ecology and Evolution"
DOI: 10.1002/ece3.70917
Abstract: ABSTRACT The cotton leafworm, Spodoptera littoralis (Lepidoptera: Noctuidae), is a major agricultural pest affecting crops like cotton, maize, tomatoes, and wheat across southern Europe, Africa, the Middle East, and western Asia. Whole genome analyses have… read more here.
Keywords: divergent selection; selection; detoxification; involvement detoxification ... See more keywords
CYP3A4/5 mediates the metabolic detoxification of humantenmine, a highly toxic alkaloid from Gelsemium elegans Benth.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.3813
Abstract: Gelsemium elegans Benth., a well‐known toxic herbal plant, is widely used to treat rheumatic arthritis, inflammation and other diseases. Gelsemium contains humantenmine (HMT), which is an important bioactive and toxic alkaloid. Cytochrome P450 enzymes (CYPs)… read more here.
Keywords: detoxification; gelsemium elegans; hmt; toxic alkaloid ... See more keywords
Detoxification of benzo[a]pyrene primarily depends on cytochrome P450, while bioactivation involves additional oxidoreductases including 5‐lipoxygenase, cyclooxygenase, and aldo‐keto reductase in the liver
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.21902
Abstract: Cytochrome P450s are involved in detoxification and activation of benzo[a]pyrene (BaP) with unclear balance and unknown contribution of other oxidoreductases. Here, we investigated the BaP and BaP‐induced mutagenicity in hepatic and extra‐hepatic tissues using hepatic… read more here.
Keywords: reductase; gpt mice; detoxification; benzo pyrene ... See more keywords
Biofilm Formation and Detoxification of Hexavalent Chromium by Bacillus subtilis: A Sustainable Approach to Bioremediation
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Basic Microbiology"
DOI: 10.1002/jobm.70022
Abstract: Hexavalent chromium [Cr(VI)] is a toxic environmental pollutant, primarily generated by industrial processes, posing a significant risk to biota. Effective detoxification of Cr(VI) is necessary before environmental discharge. This study focused on the Cr(VI) tolerance… read more here.
Keywords: hexavalent chromium; biofilm formation; bacillus subtilis; bioremediation ... See more keywords
Effect of detoxification on biological quality of wild apricot (Prunus armeniaca L.) kernel.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.9209
Abstract: BACKGROUND Despite rich source of protein and oil, wild (bitter) apricot (Prunus armeniaca L.) kernel is rarely exploited by food industries due to high amount of antinutrients and potentially toxic amygdalin. This study was aimed… read more here.
Keywords: protein; effect detoxification; quality; biological quality ... See more keywords