Xenobiotic responses in insects.
Sign Up to like & getrecommendations! Published in 2022 at "Archives of insect biochemistry and physiology"
DOI: 10.1002/arch.21869
Abstract: Insects have evolved a powerful detoxification system to protect themselves against environmental and anthropogenic xenobiotics including pesticides and nanoparticles. The resulting tolerance to insecticides is an immense problem in agriculture. In this study, we summarize… read more here.
Keywords: detoxification; insects; responses insects; response ... See more keywords
Enhanced ammonia detoxification to urea in hepatocytes transduced with human aquaporin‐8 gene
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.27901
Abstract: Hepatic ammonia detoxification to urea is critical for the prevention of hyperammonemia and neurological damage. Hepatocyte mitochondrial aquaporin‐8 (AQP8) channels have been involved in ammonia‐derived ureagenesis. Herein, we studied whether the adenoviral gene transfer of… read more here.
Keywords: detoxification urea; haqp8; detoxification; enhanced ammonia ... See more keywords
Connecting Algal Polysaccharide Degradation to Formaldehyde Detoxification
Sign Up to like & getrecommendations! Published in 2022 at "Chembiochem"
DOI: 10.1002/cbic.202200269
Abstract: Formaldehyde is a toxic metabolite that is formed in large quantities during bacterial utilization of the methoxy sugar 6‐O‐methyl‐d‐galactose, an abundant monosaccharide in the red algal polysaccharide porphyran. Marine bacteria capable of metabolizing porphyran must… read more here.
Keywords: detoxification; formaldehyde; connecting algal; algal polysaccharide ... See more keywords
Cyclic Octapeptides Composed of Two Glutathione Units Outperform the Monomer in Lead Detoxification
Sign Up to like & getrecommendations! Published in 2022 at "Chemmedchem"
DOI: 10.1002/cmdc.202200152
Abstract: A rationally‐designed scaffold of cyclic octapeptides composed of two units of the natural tripeptide glutathione (GSH) was optimized to strongly and selectively capture toxic lead ions (Pb(II)). Using state‐of‐the‐art computational tools, a list of eleven… read more here.
Keywords: detoxification; octapeptides composed; cyclic octapeptides; glutathione ... See more keywords
CYP3A4/5 mediates the metabolic detoxification of humantenmine, a highly toxic alkaloid from Gelsemium elegans Benth.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.3813
Abstract: Gelsemium elegans Benth., a well‐known toxic herbal plant, is widely used to treat rheumatic arthritis, inflammation and other diseases. Gelsemium contains humantenmine (HMT), which is an important bioactive and toxic alkaloid. Cytochrome P450 enzymes (CYPs)… read more here.
Keywords: detoxification; gelsemium elegans; hmt; toxic alkaloid ... See more keywords
Detoxification of benzo[a]pyrene primarily depends on cytochrome P450, while bioactivation involves additional oxidoreductases including 5‐lipoxygenase, cyclooxygenase, and aldo‐keto reductase in the liver
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.21902
Abstract: Cytochrome P450s are involved in detoxification and activation of benzo[a]pyrene (BaP) with unclear balance and unknown contribution of other oxidoreductases. Here, we investigated the BaP and BaP‐induced mutagenicity in hepatic and extra‐hepatic tissues using hepatic… read more here.
Keywords: reductase; gpt mice; detoxification; benzo pyrene ... See more keywords
Effect of detoxification on biological quality of wild apricot (Prunus armeniaca L.) kernel.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.9209
Abstract: BACKGROUND Despite rich source of protein and oil, wild (bitter) apricot (Prunus armeniaca L.) kernel is rarely exploited by food industries due to high amount of antinutrients and potentially toxic amygdalin. This study was aimed… read more here.
Keywords: protein; effect detoxification; quality; biological quality ... See more keywords
Susceptibilities of Candidatus Liberibacter asiaticus‐infected and noninfected Diaphorina citri to entomopathogenic fungi and their detoxification enzyme activities under different temperatures
Sign Up to like & getrecommendations! Published in 2018 at "MicrobiologyOpen"
DOI: 10.1002/mbo3.607
Abstract: Some entomopathogenic fungi species, Isaria fumosorosea, and Hirsutella citriformis were found to be efficient against the Asian citrus psyllid, Diaphorina citri Kuwayama (Hemiptera: Liviidae). However, the susceptibility to these fungi increases when the psyllid infected… read more here.
Keywords: detoxification; entomopathogenic fungi; candidatus liberibacter; liberibacter asiaticus ... See more keywords
Functional validation of CYP304A1 associated with haedoxan A detoxification in Aedes albopictus by RNAi and transgenic Drosophila.
Sign Up to like & getrecommendations! Published in 2022 at "Pest management science"
DOI: 10.1002/ps.7213
Abstract: BACKGROUND Insect cytochrome P450 monooxygenases play important roles in the detoxification metabolism of endogenous and exogenous compounds. Haedoxan A (HA) from Phryma leptostachya L. is a highly efficient natural pesticide used to control houseflies and… read more here.
Keywords: detoxification; cyp304a1; expression; validation cyp304a1 ... See more keywords
Ampicillin enhanced the resistance of Myzus persicae to imidacloprid and cyantraniliprole.
Sign Up to like & getrecommendations! Published in 2022 at "Pest management science"
DOI: 10.1002/ps.7310
Abstract: BACKGROUND Recent studies have shown that symbionts are involved in regulating insecticide detoxification in insects. However, there are few studies on the relationship between the symbionts found in Myzus persicae and the mechanism underlying host… read more here.
Keywords: detoxification; persicae; ampicillin; imidacloprid cyantraniliprole ... See more keywords
Linker Independent Regioselective Protonation Triggered Detoxification of Sulfur Mustards with Smart Porous Organic Photopolymer.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202302045
Abstract: The development of efficient metal-free photocatalysts for the generation of reactive oxygen species (ROS) for sulfur mustard (HD) decontamination can play a vital role against the stockpiling of chemical warfare agents (CWAs). Herein, one novel… read more here.
Keywords: detoxification; regioselective protonation; protonation; independent regioselective ... See more keywords