Detrimental influence of Arginase-1 in infiltrating macrophages on poststroke functional recovery and inflammatory milieu
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DOI: 10.1073/pnas.2413484122
Abstract: Significance Ischemic stroke remains a leading cause of long-term disability worldwide. While Arginase-1 (Arg1) expressing macrophages are typically associated with anti-inflammatory responses and tissue repair, we reveal an unexpected detrimental influence of Arg1 on poststroke… read more here.
Keywords: functional recovery; infiltrating macrophages; detrimental influence; recovery ... See more keywords