The effect of combined treatment with a β3AR agonist and a ROCK inhibitor on detrusor overactivity
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DOI: 10.1002/nau.22978
Abstract: The objective of the study was to evaluate the efficacy and safety of the combined treatment with the β3AR agonist and ROCK inhibitor in the rat model of detrusor overactivity induced by retinyl acetate instillation. read more here.
Keywords: detrusor overactivity; rock inhibitor; 3ar agonist; agonist rock ... See more keywords
Comparison of the effectiveness of repeated injections of onabotulinum toxin A for refractory idiopathic detrusor overactivity: analysis of an open label extension of a randomized trial (the RELAX study)
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DOI: 10.1002/nau.23095
Abstract: To assess effects of repeat treatment with onabotulinumtoxin A (onaBoNT‐A) in women with refractory idiopathic detrusor overactivity (DO). read more here.
Keywords: detrusor overactivity; refractory idiopathic; idiopathic detrusor; comparison effectiveness ... See more keywords
Efficacy and safety of mirabegron for the treatment of neurogenic detrusor overactivity—Prospective, randomized, double‐blind, placebo‐controlled study
Sign Up to like & getrecommendations! Published in 2018 at "Neurourology and Urodynamics"
DOI: 10.1002/nau.23566
Abstract: To assess the efficacy and safety of mirabegron in the treatment of neurogenic detrusor overactivity. read more here.
Keywords: treatment neurogenic; mirabegron treatment; efficacy safety; neurogenic detrusor ... See more keywords
Neural or “Moral” therapy in the treatment of neurogenic detrusor overactivity in multiple sclerosis patients
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DOI: 10.1002/nau.23589
Abstract: – First, in the statistical analysis section, the authors stated that they had used Student t-test or theMannWhitney U test for variables with or without normal distribution, respectively. Nonetheless, these two tests are used to… read more here.
Keywords: detrusor overactivity; treatment; therapy; test ... See more keywords
Vascular measures of atherosclerosis in detrusor overactivity and controls
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DOI: 10.1002/nau.23784
Abstract: The mechanisms leading to the development of detrusor overactivity (DO) are still relatively poorly understood, however, animal studies suggest that atherosclerosis and reduced blood flow to the bladder may be one etiological pathway. Thus, the… read more here.
Keywords: vascular measures; measures atherosclerosis; overactivity; detrusor overactivity ... See more keywords
Effects of early intravesical administration of resiniferatoxin to spinal cord‐injured rats in neurogenic detrusor overactivity
Sign Up to like & getrecommendations! Published in 2019 at "Neurourology and Urodynamics"
DOI: 10.1002/nau.24032
Abstract: To investigate if intravesical administration during spinal shock of resiniferatoxin (RTX), an ultrapotent desensitizing agonist of transient receptor potential vanilloid‐1 (TRPV1), would silence TRPV1‐expressing bladder afferents at an early stage of disease progression and modulate… read more here.
Keywords: neurogenic detrusor; intravesical administration; detrusor overactivity; resiniferatoxin ... See more keywords
Efficacy and safety of mirabegron in children and adolescents with neurogenic detrusor overactivity: An open‐label, phase 3, dose‐titration study
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DOI: 10.1002/nau.24657
Abstract: To evaluate the efficacy and safety of mirabegron in children and adolescents (aged 3 to read more here.
Keywords: efficacy safety; neurogenic detrusor; safety mirabegron; children adolescents ... See more keywords
The intracerebroventricular injection of lipopolysaccharide may induce neurogenic detrusor overactivity symptoms in mice
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DOI: 10.1002/nau.24890
Abstract: We aimed to explore if the intracerebroventricular (i.c.v.) injection of lipopolysaccharide (LPS) was able to evoke the cognitive and locomotive impairment and detrusor overactivity (DO) symptoms in mice. read more here.
Keywords: intracerebroventricular injection; symptoms mice; overactivity symptoms; detrusor overactivity ... See more keywords
Is coital incontinence a manifestation of urodynamic stress incontinence or detrusor overactivity?
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DOI: 10.1007/s00192-021-04809-8
Abstract: Coital incontinence (CI) is an underreported symptom among sexually active women. It has been assumed that incontinence at penetration (CIAP) is due to urodynamic stress incontinence (USI), while coital incontinence at orgasm (CIAO) is thought… read more here.
Keywords: stress incontinence; incontinence; ciao; detrusor overactivity ... See more keywords
Involvement of TRPM4 in detrusor overactivity following spinal cord transection in mice
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DOI: 10.1007/s00210-018-1542-0
Abstract: Transient receptor potential cation channel subfamily M member 4 (TRPM4) has been shown to play a key role in detrusor contractility under physiological conditions. In this study, we investigated the potential role of TRPM4 in… read more here.
Keywords: following spinal; detrusor; trpm4; detrusor overactivity ... See more keywords
Intravesical oxybutynin therapy for patients with neurogenic detrusor overactivity: a systematic review and meta-analysis
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DOI: 10.1007/s11255-022-03129-0
Abstract: To evaluate the effectiveness and safety of intravesical oxybutynin therapy for patients with neurogenic detrusor overactivity. A systematic search in PubMed, MEDLINE, EMBASE, ClinicalTrial.gov, and Cochrane Controlled Trials Register was conducted from 1990 to 2021.… read more here.
Keywords: oxybutynin; intravesical oxybutynin; detrusor overactivity; neurogenic detrusor ... See more keywords