The deubiquitinase UCHL5/UCH37 positively regulates Hedgehog signaling by deubiquitinating Smoothened
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Molecular Cell Biology"
DOI: 10.1093/jmcb/mjx036
Abstract: The Hedgehog (Hh) signaling pathway plays important roles in developmental processes including pattern formation and tissue homeostasis. The seven-pass transmembrane receptor Smoothened (Smo) is the pivotal transducer in the pathway; it, and thus the pathway… read more here.
Keywords: hedgehog signaling; regulates hedgehog; deubiquitinase uchl5; uch37 positively ... See more keywords