Deubiquitinase USP12 promotes LPS induced macrophage responses through inhibition of IκBα.
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DOI: 10.1016/j.bbrc.2017.01.004
Abstract: Post translational modifications, ubiquitination and its reversal by deubiquitination play an important role in regulating innate immune system. USP12 is a poorly studied deubiquitinase reported to regulate T-cell receptor signalling however the functional role of… read more here.
Keywords: lps induced; usp12 promotes; macrophage; deubiquitinase usp12 ... See more keywords