The emerging role of deubiquitylating enzymes as therapeutic targets in cancer metabolism
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Cell International"
DOI: 10.1186/s12935-022-02524-y
Abstract: Cancer cells must rewire cellular metabolism to satisfy the unbridled proliferation, and metabolic reprogramming provides not only the advantage for cancer cell proliferation but also new targets for cancer treatment. However, the plasticity of the… read more here.
Keywords: cancer; cancer cell; targets cancer; cancer metabolism ... See more keywords
ABPP-HT*—Deep Meets Fast for Activity-Based Profiling of Deubiquitylating Enzymes Using Advanced DIA Mass Spectrometry Methods
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DOI: 10.3390/ijms23063263
Abstract: Activity-based protein profiling (ABPP) uses a combination of activity-based chemical probes with mass spectrometry (MS) to selectively characterise a particular enzyme or enzyme class. ABPP has proven invaluable for profiling enzymatic inhibitors in drug discovery.… read more here.
Keywords: activity based; profiling deubiquitylating; mass spectrometry; activity ... See more keywords