A sensitive method for determining UDP-glucose: ceramide glucosyltransferase (UGCG) activity in biological samples using deuterated glucosylceramide as acceptor substrate.
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DOI: 10.1093/glycob/cwac081
Abstract: Glucosylceramide synthase (UGCG) is a key enzyme in the biosynthesis of glycosphingolipids and its activity is related to the resistance to anticancer drugs and is involved in the derangement of metabolism in various diseases. Moreover,… read more here.
Keywords: using deuterated; method determining; deuterated glucosylceramide; activity ... See more keywords