Site-selective deuteration of N-heterocycles via iridium-catalyzed hydrogen isotope exchange
Sign Up to like & getrecommendations! Published in 2017 at "ACS Catalysis"
DOI: 10.1021/acscatal.7b02682
Abstract: The application of iridium(I) NHC/phosphine catalysts has delivered highly selective deuteration of indole, azaindole, and pyrrole N-heterocycles, which represent an important and relatively underexplored class of labeling substrates. Common N-protecting groups have been used to… read more here.
Keywords: selective deuteration; site selective; iridium; deuteration heterocycles ... See more keywords