15N transverse relaxation measurements for the characterization of µs–ms dynamics are deteriorated by the deuterium isotope effect on 15N resulting from solvent exchange
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biomolecular NMR"
DOI: 10.1007/s10858-018-0211-4
Abstract: Abstract15N R2 relaxation measurements are key for the elucidation of the dynamics of both folded and intrinsically disordered proteins (IDPs). Here we show, on the example of the intrinsically disordered protein α-synuclein and the folded… read more here.
Keywords: relaxation measurements; deuterium isotope; relaxation; exchange ... See more keywords
Solvent Deuterium Isotope Effects of Substrate Reduction by Nitrogenase from Azotobacter vinelandii
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c07574
Abstract: The mechanism of nitrogenase, the enzyme responsible for biological nitrogen fixation, has been of great interest for understanding the catalytic strategy utilized to reduce dinitrogen to ammonia under ambient temperatures and pressures. The reduction mechanism… read more here.
Keywords: deuterium isotope; nitrogenase; isotope effects; isotope ... See more keywords