Multifaceted Nano-DEV-IL for Sustained Release of IL-12 to Avert the Immunosuppressive Tumor Microenvironment and IL-12-Associated Toxicities.
Sign Up to like & getrecommendations! Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.3c02934
Abstract: Interleukin-12 (IL-12) demonstrates potent antitumor activity by enhancing Th1/Th2 response, facilitating cytotoxic T-cell (CTL) recruitment into tumors, inhibiting tumor angiogenesis, and depleting immunosuppressive cells in the tumor microenvironment (TME). Despite having encouraging preclinical and some… read more here.
Keywords: nano dev; dev; tumor microenvironment; multifaceted nano ... See more keywords
Systematic analysis of the Myxococcus xanthus developmental gene regulatory network supports posttranslational regulation of FruA by C‐signaling
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Microbiology"
DOI: 10.1111/mmi.14249
Abstract: Upon starvation Myxococcus xanthus undergoes multicellular development. Rod‐shaped cells move into mounds in which some cells differentiate into spores. Cells begin committing to sporulation at 24–30 h poststarvation, but the mechanisms governing commitment are unknown.… read more here.
Keywords: myxococcus xanthus; developmental gene; dev; frua ... See more keywords