Multifaceted Nano-DEV-IL for Sustained Release of IL-12 to Avert the Immunosuppressive Tumor Microenvironment and IL-12-Associated Toxicities.
Sign Up to like & getrecommendations! Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.3c02934
Abstract: Interleukin-12 (IL-12) demonstrates potent antitumor activity by enhancing Th1/Th2 response, facilitating cytotoxic T-cell (CTL) recruitment into tumors, inhibiting tumor angiogenesis, and depleting immunosuppressive cells in the tumor microenvironment (TME). Despite having encouraging preclinical and some… read more here.
Keywords: nano dev; dev; tumor microenvironment; multifaceted nano ... See more keywords
Novel mixed approximate deconvolution subgrid-scale models for large-eddy simulation
Sign Up to like & getrecommendations! Published in 2024 at "Physics of Fluids"
DOI: 10.1063/5.0221814
Abstract: Approximate deconvolution (AD) has emerged as a promising closure for large-eddy simulation in complex multi-physics flows, where the conventional pure dynamic eddy-viscosity (DEV) models experience issues. In this research, we propose novel improved mixed hard-deconvolution… read more here.
Keywords: approximate deconvolution; large eddy; dev; eddy simulation ... See more keywords
Pathogenic mechanisms and molecular features of a novel UL2 gene-deficient duck enteritis virus endemic to China
Sign Up to like & getrecommendations! Published in 2025 at "Virulence"
DOI: 10.1080/21505594.2025.2547325
Abstract: ABSTRACT Duck enteritis virus (DEV) was identified as the etiological agent responsible for an outbreak of morbidity and mortality in adult ducks on a farm in Jiangsu, China. Diagnostic approaches confirmed that the outbreak was… read more here.
Keywords: virulent; enteritis virus; dev; duck enteritis ... See more keywords
Systematic analysis of the Myxococcus xanthus developmental gene regulatory network supports posttranslational regulation of FruA by C‐signaling
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Microbiology"
DOI: 10.1111/mmi.14249
Abstract: Upon starvation Myxococcus xanthus undergoes multicellular development. Rod‐shaped cells move into mounds in which some cells differentiate into spores. Cells begin committing to sporulation at 24–30 h poststarvation, but the mechanisms governing commitment are unknown.… read more here.
Keywords: myxococcus xanthus; developmental gene; dev; frua ... See more keywords