How many people develop anti‐drug antibodies to the biologic drug tildrakizumab, and what impact does this have on the effectiveness of their treatment
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Dermatology"
DOI: 10.1111/bjd.18662
Abstract: Biologics are powerful drugs used to treat a range of diseases including psoriasis. They can be very effective; however, the body's immune system, which normally fights off infection, can produce ‘anti‐drug antibodies’ (or ADAs) that… read more here.
Keywords: develop anti; drug antibodies; drug; many people ... See more keywords
Targeting the BspC-vimentin interaction to develop anti-virulence therapies during Group B streptococcal meningitis
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1010397
Abstract: Bacterial infections are a major cause of morbidity and mortality worldwide and the rise of antibiotic resistance necessitates development of alternative treatments. Pathogen adhesins that bind to host cells initiate disease pathogenesis and represent potential… read more here.
Keywords: interaction; anti virulence; meningitis; group ... See more keywords