A minimalistic approach to develop new anti-apicomplexa polyamines analogs.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2017.11.069
Abstract: The development of new chemical entities against the major diseases caused by parasites is highly desired. A library of thirty diamines analogs following a minimalist approach and supported by chemoinformatics tools have been prepared and… read more here.
Keywords: approach develop; develop new; new anti; anti apicomplexa ... See more keywords
The Need For Physiological Phenotyping To Develop New Drugs For Airways Disease.
Sign Up to like & getrecommendations! Published in 2020 at "Pharmacological research"
DOI: 10.1016/j.phrs.2020.105029
Abstract: Asthma and COPD make up the majority of obstructive airways diseases (OADs), which affects ∼11% of the population. The main drugs used to treat OADs have not changed in the past five decades, with advancements… read more here.
Keywords: drugs airways; physiological phenotyping; develop new; phenotyping develop ... See more keywords
Educating engineers to develop new business models: Exploiting entrepreneurial opportunities in technology-based firms
Sign Up to like & getrecommendations! Published in 2018 at "Technological Forecasting and Social Change"
DOI: 10.1016/j.techfore.2018.11.011
Abstract: Abstract This study examines educational frameworks and practices useful in teaching engineers to develop new business models (BM) that exploit entrepreneurial opportunities in technology-based firms. We compare three existing frameworks (Blue Ocean, the Business Model… read more here.
Keywords: develop new; business model; new business; business ... See more keywords
A needs analysis to develop new curriculum for Korean college students in higher education
Sign Up to like & getrecommendations! Published in 2022 at "Indonesian Journal of Applied Linguistics"
DOI: 10.17509/ijal.v12i1.46564
Abstract: Language teachers and instructors should always consider how to successfully develop new curricula. A medium-sized university in Korea launched a new liberal arts course for freshmen. A language instructor conducted a need analysis to understand… read more here.
Keywords: college students; new curriculum; language; develop new ... See more keywords
Naphthoquinone Derivatives as Scaffold to Develop New Drugs for Tuberculosis Treatment
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2018.00673
Abstract: Despite being a curable disease, tuberculosis (TB) remains a public health problem worldwide mainly due to lengthy treatment, as well as its toxic effects, TB/HIV co-infection and the emergence of resistant Mycobacterium tuberculosis strains. These… read more here.
Keywords: develop new; treatment; derivatives scaffold; naphthoquinone derivatives ... See more keywords
Metabolomics as a Crucial Tool to Develop New Therapeutic Strategies for Neurodegenerative Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Metabolites"
DOI: 10.3390/metabo12090864
Abstract: Neurodegenerative diseases (NDs), such as Alzheimer’s (AD), Parkinson’s (PD), and amyotrophic lateral sclerosis (ALS), share common pathological mechanisms, including metabolism alterations. However, their specific neuronal cell types affected and molecular biomarkers suggest that there are… read more here.
Keywords: new therapeutic; tool develop; develop new; metabolomics crucial ... See more keywords