Albumin roles in developing anticancer compounds
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DOI: 10.1007/s00044-021-02748-z
Abstract: Albumin is an abundant protein in nature with several biological functions. In the human body, both in health and in illness, its transport function is highlighted by the binding to medicinal drugs and consequent distribution… read more here.
Keywords: albumin; roles developing; chemistry; developing anticancer ... See more keywords
Developing an Anticancer Platinum(II) Compound Based on the Uniqueness of Human Serum Albumin.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.3c00001
Abstract: To develop the next-generation Pt drug with remarkable activity and low toxicity to maximally inhibit tumor growth, we optimized a Pt(II) thiosemicarbazone compound (C4) with remarkable cytotoxicity to SK-N-MC cells and then constructed a new… read more here.
Keywords: serum albumin; developing anticancer; compound; human serum ... See more keywords